Equinixin 2.5% Granules – 10x10g
- Equinixin Granules for Horses is a powerful non-steroidal anti-inflammatory drug (NSAID). It is formulated to treat musculoskeletal disorders in horses, such as laminitis and osteoarthritis. It is easy to administer because it is given by mixing it in a small feed. Flunixin is an anti-inflammatory, analgesic (pain relief), antipyretic (reduces fever) and is also anti-endotoxic (reduces toxin). It works by preventing the body from synthesizing prostaglandins that relieve pain and cause inflammatory processes and pyrogens (substances that cause fever). Two bags offer a day treatment for an average of 454 kg of the horse. Each 10 g sachet contains 250 mg flunixin meglumine. Available in packs of 10 bags.
Equinixin Granules for Horses is an anti-inflammatory, analgesic (pain relief), antipyretic (reduces fever) and is also anti-endotoxic (reduces toxin). It works by preventing the body from synthesizing prostaglandins that relieve pain and cause inflammatory processes and pyrogens (substances that cause fever). Ekvinixin 2.5% granulate is indicated for oral administration to horses. Easily served by spraying small amounts of food. Add to feed immediately before administration. Discard medicinal feed residues. The recommended dose is one bag (10 grams) of ecvinixin granules per 227 kg (500 lbs) of body weight (equivalent to 1.1 mg of flunixin per kg) once a day for up to 5 consecutive days, depending on the clinical response.
Equinixin Granules for Horses meglumine acts as a reversible, non-selective cyclooxygenase inhibitor (both COX 1 and COX 2 forms), an important enzyme in the arachidonic acid cascade that is responsible for converting arachidonic acid into cyclic endoperoxides. As a result, the synthesis of eicosanoids, important mediators of the inflammatory process involved in central pyrosis, pain perception, and tissue inflammation, is inhibited. Due to its effect on the arachidonic acid cascade, flunixin also inhibits the production of thromboxane, a potent platelet praggregator and a vasoconstrictor that is released during blood clotting. Flunixin exerts its antipyretic effect by inhibiting the synthesis of prostaglandin E2 in the hypothalamus. Although flunixin has no direct effect on endotoxins after they have been formed, it reduces prostaglandin production and therefore reduces many of the effects of the prostaglandin cascade. Prostaglandins are part of the complex processes involved in the development of endotoxic shock.
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