Genestran 75mg/ml Solution for Injection 20ml


Genestran is used in reproductive medicine in horses and contains cloprostenol, a synthetic Prostaglandin F 2a. It is designed to induce luteolysis, destruction of the corpus luteum, so that oestrus and ovulation can occur in cyclic mares. It is also licenced for use as a reproductive medicine of cattle and pigs.



Genestran 75mg/ml Solution for Injection 20ml is used to induce luteolysis in mares with functional corpus luteum. Warnings and contraindications Light sweating and diarrhea may develop temporarily. Handle the product with care and avoid skin contact or self-injection. Pregnancy and breastfeeding Only give pregnant mares if they plan to cause miscarriage or give birth. Consult your veterinarian for advice while breastfeeding. This medicine cannot be used in horses for human consumption.

Genestran 75mg/ml Solution for Injection 20ml direct contact with skin or mucous membranes of the user should be avoided. Prostaglandins of the F2α type may be absorbed through the skin and may cause bronchospasm or miscarriage. Care should be taken when handling the product to avoid self-injection or skin contact. Pregnant women, women of childbearing age, asthmatics and persons with other respiratory tract diseases should exercise caution when handling cloprostenol. Those persons should wear gloves during the administration of the product. Accidental spillage on the skin should be washed immediately with soap and water. In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.


– induction of luteolysis allowing resumption of oestrus and ovulation in cyclic females when used during dioestrus
– the synchronisation of oestrus (within 2 to 5 days) in groups of cyclic females treated simultaneously
– treatment of suboestrus and uterine disorders related to a functioning or persistent corpus luteum (endometritis, pyometra)
– treatment of ovarian luteal cysts
– induction of abortion until day 150 of pregnancy
– expulsion of mummified fetuses
– induction of parturition (within the last two weeks of gestation).

– induction of luteolysis in mares with a functional corpus luteum.

– induction or synchronization of farrowing (generally within 24 to 36 hours) from day 113 of pregnancy onwards (day 1 of pregnancy is the last day of natural or artificial insemination).


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